Maxwell G F, Lemij H G, Collewijn H
Department of Physiology, Erasmus University, Rotterdam, The Netherlands.
Invest Ophthalmol Vis Sci. 1995 Nov;36(12):2514-22.
To determine the degree of conjugacy of saccades in humans with one deeply amblyopic eye, to assess whether Hering's law requires good binocular visual acuity.
By means of magnetic search coils, horizontal saccades were recorded accurately in 11 subjects with unilateral, deep amblyopia. The recordings were compared to those made in 11 normal subjects. In addition, three subjects with amblyopia were submitted to artificial anisometropia, which called for nonconjugate adaptation of their saccades.
The saccades of most subjects with amblyopia were nonconjugate. These nonconjugacies often were larger in one direction than in the opposite one. The magnitude of the nonconjugacies varied inconsistently with the size of the saccades. In addition, the amblyopic eye often showed conspicuous drift. The saccades adapted nonconjugately to the imposed anisometropia.
In deep amblyopia, the two eyes often make saccades that are unequal in size. The amblyopic eye does not move aimlessly, roughly following the movements of the normal fellow eye. Instead, the saccades of the amblyopic eye appear to reflect a deliberate oculomotor strategy, bringing visual targets to presumed retinal points of preference.
确定单眼深度弱视患者扫视的共轭程度，评估赫林定律是否需要良好的双眼视力。
通过磁搜索线圈，精确记录了11名单侧深度弱视患者的水平扫视。将记录结果与11名正常受试者的记录结果进行比较。此外，对3名弱视患者进行了人工屈光参差处理，这需要他们的扫视进行非共轭适应。
大多数弱视患者的扫视是非共轭的。这些非共轭在一个方向上通常比在相反方向上更大。非共轭的程度与扫视的大小不一致。此外，弱视眼经常出现明显的漂移。扫视对施加的屈光参差进行了非共轭适应。
在深度弱视中，双眼的扫视大小往往不相等。弱视眼并非无目的地大致跟随健眼的运动。相反，弱视眼的扫视似乎反映了一种刻意的眼球运动策略，将视觉目标带到假定的视网膜偏好点。
