Mullally B H, James J A, Coulter W A, Linden G J
Division of Restorative Dentistry (Periodontics), School of Clinical Dentistry, Queen's University, Belfast, Northern Ireland, UK.
J Clin Periodontol. 1995 Sep;22(9):686-9. doi: 10.1111/j.1600-051x.1995.tb00827.x.
A double-blind controlled clinical trial with parallel groups was designed to investigate the effectiveness of a herbal-based toothpaste in the control of plaque and gingivitis as compared with a conventional dentifrice. 70 subjects with gingivitis completed the 6-week study. All participants had at least 20 natural teeth with no probing depths greater than 3 mm and a plaque index of 2 or more at baseline. At baseline, both groups were balanced for the parameters measured: plaque index, plaque vitality, gingival index, bleeding on probing and gingival crevicular fluid flow. At the end of the trial, there were reductions within both groups, however, there were no significant differences between the groups. It was concluded that the herbal based toothpaste was as effective as the conventionally formulated dentifrice in the control of plaque and gingivitis.
设计了一项双盲平行组对照临床试验,以研究一种草本牙膏与传统牙膏相比在控制牙菌斑和牙龈炎方面的有效性。70名患有牙龈炎的受试者完成了为期6周的研究。所有参与者至少有20颗天然牙,基线时探诊深度不超过3mm,菌斑指数为2或更高。在基线时,两组在以下测量参数上是平衡的:菌斑指数、菌斑活力、牙龈指数、探诊出血和龈沟液流量。试验结束时,两组均有减少,但两组之间无显著差异。得出的结论是,草本牙膏在控制牙菌斑和牙龈炎方面与传统配方牙膏同样有效。