Huland H, Buchardt P, Köllermann M, Augustin J
J Urol. 1979 Jan;121(1):10-2. doi: 10.1016/s0022-5347(17)56641-0.
Of 85 adults with end stage renal disease examined consecutively for renal transplantation 25 (29.4 per cent) had vesicoureteral reflux. Of these 25 patients 11 had a nephropathy as the cause of renal failure that was unrelated to reflux (for example glomerulonephritis) and 12 had, in addition to vesicoureteral reflux, a history of urinary tract infections and chronic pyelonephritis, which seems to be significant in the etiology of terminal renal failure in our patients (14 per cent). Only 2 of the 25 patients had severe, sterile reflux: 1 had bilateral megaureter with reflux into 1 side after ureteroneocystostomy and 1 had bilateral grade IV sterile reflux complicated by megacystitis. We had no case of uncomplicated, sterile reflux, which, in our experience, seems to be a rare cause of renal failure.
在连续接受肾移植检查的85例终末期肾病成人患者中，25例（29.4%）存在膀胱输尿管反流。在这25例患者中，11例的肾衰竭病因是与反流无关的肾病（如肾小球肾炎），12例除膀胱输尿管反流外，还有尿路感染和慢性肾盂肾炎病史，这在我们患者的终末期肾衰竭病因中似乎具有重要意义（14%）。25例患者中只有2例有严重的无菌性反流：1例在输尿管膀胱吻合术后双侧巨输尿管伴一侧反流，1例双侧IV级无菌性反流并伴有巨膀胱炎。我们没有单纯性无菌性反流的病例，根据我们的经验，这似乎是肾衰竭的罕见病因。
