Márk L, Orosz I, Ottlakán A, Wolf I
Kardiológiai Rehabilitációs Osztály, Békés Megyei Képviselötestület Pándy Kálmán Kórház, Gyula.
Orv Hetil. 1995 Jun 11;136(24):1267-9.
In the treatment of hyperlipoproteinaemia the diet still has a primary importance. The authors have investigated the effect of different fat, cholesterol and unsaturated/saturated fatty acid content diets on the lipid levels of men suffering from coronary heart disease during 3 weeks long hospital treatment in the Cardiac Rehabilitation Department. On a diet containing daily 65 g fat, 230 mg cholesterol with a 1.23 unsaturated/saturated fatty acid ratio the total cholesterol level of 66 patients showed a 5.8% decrease (P < 0.05). The 1% decrease of triglyceride, the 3.9% decrease of HDL-cholesterol, the 7.3% decrease of LDL-cholesterol levels were not significant. There was a positive correlation between the cholesterol level at the beginning and the degree of its change (0.7043): the patients with 6.5 mmol/l or less cholesterol level at the entry in the study showed a 2.8% decrease in serum cholesterol level, the patients with more than 6.5 mmol/l 8.1%. On a diet containing daily 105 g fat, 420 mg cholesterol, with a 0.7 unsaturated/saturated fatty acid ratio the triglyceride level showed a 20.6%, the total cholesterol 0.5% increase, at the same hand the HDL-cholesterol 1.1%, the LDL-cholesterol 5.1% decrease (only the change of triglyceride level was significant). The results emphasise the strong relation between diet and level of serum lipids.
在高脂蛋白血症的治疗中，饮食仍然至关重要。作者研究了不同脂肪、胆固醇以及不饱和/饱和脂肪酸含量的饮食，对冠心病男性患者在心脏康复科进行为期3周的住院治疗期间血脂水平的影响。在每日含有65克脂肪、230毫克胆固醇且不饱和/饱和脂肪酸比例为1.23的饮食条件下，66名患者的总胆固醇水平下降了5.8%（P < 0.05）。甘油三酯水平下降1%、高密度脂蛋白胆固醇水平下降3.9%、低密度脂蛋白胆固醇水平下降7.3%，差异均无统计学意义。初始胆固醇水平与其变化程度之间存在正相关（0.7043）：研究开始时胆固醇水平在6.5 mmol/l及以下的患者，血清胆固醇水平下降了2.8%，而胆固醇水平高于6.5 mmol/l的患者下降了8.1%。在每日含有105克脂肪、420毫克胆固醇且不饱和/饱和脂肪酸比例为0.7的饮食条件下，甘油三酯水平上升了20.6%，总胆固醇上升了0.5%，同时高密度脂蛋白胆固醇上升了1.1%，低密度脂蛋白胆固醇下降了5.1%（只有甘油三酯水平的变化具有统计学意义）。结果强调了饮食与血脂水平之间的密切关系。
