Livanova L M, Nozdracheva L V, Kurochkina E V, Aĭrapetiants M G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Mar-Apr;45(2):402-9.
The work was carried out in 98 white male rats weighting 200-250 g. Typological properties of behaviour were estimated by locomotor activity in the open field. Neurosis was induced by electro-pain irritation (15 min daily during 3 weeks), accompanied by the white noise (4 h daily). The rats were influenced by air ions generated by Chizhevsky air ionizer ("Elion-132") for 2 h daily during the period of neurotization. It was shown that the degree of some pathological changes in neurosis depended on typological properties of rats. Air ions were established to prevent completely development of physiological changes typical for the model of experimental neuroses, i.e., increase of arterial pressure, Hildebrandt index and gastric ulcer formation. Air ions significantly decreased the number of gastric mucous membrane erosions. Air ions normalized activity of respiratory enzymes (succinate dehydrogenase and NADH-dehydrogenase) in rat brain cells and activated their exploratory behaviour.
该实验以98只体重为200 - 250克的雄性白鼠为对象进行。通过旷场实验中的运动活动来评估行为的类型学特征。采用电刺激疼痛(每天15分钟,持续3周)并伴有白噪音(每天4小时)诱导神经症。在神经症形成期间,每天用奇热夫斯基空气离子发生器(“Elion - 132”)产生的空气离子对大鼠进行2小时的处理。结果表明,神经症中某些病理变化的程度取决于大鼠的类型学特征。已证实空气离子可完全防止实验性神经症模型典型的生理变化的发展,即动脉血压升高、希尔德布兰特指数升高和胃溃疡形成。空气离子显著减少了胃黏膜糜烂的数量。空气离子使大鼠脑细胞中呼吸酶(琥珀酸脱氢酶和NADH脱氢酶)的活性恢复正常,并激活了它们的探索行为。