Busse W W, Coffman R L, Gelfand E W, Kay A B, Rosenwasser L J
Am J Respir Crit Care Med. 1995 Jul;152(1):388-93. doi: 10.1164/ajrccm.152.1.7599853.
The role of T cells in human allergic inflammation is just beginning to be understood. However, the data presented indicate how the T cell may be a pivotal cell to direct features of allergic inflammation in asthma, how the T cell may be able to transfer hyperresponsiveness, which is a feature of bronchial asthma, what some of the genetic factors are that may determine this process, and how an important precipitant of asthma, viral respiratory infections, may participate in this process. Its cells are isolated from patients with asthma and studied for their ability to generate proinflammatory failure. An expanded understanding of the chronic, persistent nature of asthma will become apparent.
T细胞在人类过敏性炎症中的作用才刚刚开始被了解。然而，所呈现的数据表明T细胞可能是指导哮喘过敏性炎症特征的关键细胞，T细胞如何能够传递作为支气管哮喘特征的高反应性，哪些遗传因素可能决定这一过程，以及哮喘的重要诱发因素——病毒性呼吸道感染——如何参与这一过程。从哮喘患者中分离出其细胞，并研究它们产生促炎功能障碍的能力。对哮喘慢性、持续性本质的更广泛理解将变得明显。
