Gardner D G
Division of Oral Pathology and Oncology, University of Colorado School of Dentistry, USA.
J Oral Pathol Med. 1996 Jan;25(1):32-7. doi: 10.1111/j.1600-0714.1996.tb01220.x.
This article is based on a review of the literature and the study of pathology sections obtained from various veterinary pathology laboratories. Epulis is a non-specific, clinical designation for a localized, exophytic growth on the gingiva. Four reactive epulides occur in human beings, namely focal fibrous hyperplasia (fibrous epulis), pyogenic granuloma, peripheral giant cell granuloma (giant cell epulis), and peripheral ossifying fibroma (calcifying fibrous epulis). The first three also occur in dogs but only focal fibrous hyperplasia appears to be common. The peripheral ossifying fibroma has not yet been reported in dogs. Odontogenic tumors occurring on the gingiva (i.e., as epulides) are referred to as peripheral odontogenic tumors. Three types have been reported in dogs. One, the common fibromatous epulis, is equivalent to the rare peripheral odontogenic fibroma in human beings. Another, the acanthomatous epulis, appears to be a form of ameloblastoma but differs from the peripheral ameloblastoma in human beings in that it invades bone; its biological behavior is therefore that of the human intraosseous ameloblastoma. The third, a rare lesion, has been referred to in the veterinary literature as a calcifying epithelial odontogenic tumor, although it is not the canine counterpart of the human CEOT. The term, amyloid-producing odontogenic tumor, has been suggested as being appropriate for this lesion.
本文基于对文献的综述以及对从各个兽医病理学实验室获取的病理切片的研究。龈瘤是牙龈上局限性外生性生长的一种非特异性临床称谓。人类有四种反应性龈瘤，即局灶性纤维增生（纤维性龈瘤）、化脓性肉芽肿、外周性巨细胞肉芽肿（巨细胞龈瘤）和外周骨化性纤维瘤（钙化性纤维龈瘤）。前三种在犬类中也会出现，但似乎只有局灶性纤维增生较为常见。外周骨化性纤维瘤在犬类中尚未见报道。发生在牙龈上（即作为龈瘤）的牙源性肿瘤被称为外周性牙源性肿瘤。犬类中已报道有三种类型。一种是常见的纤维瘤性龈瘤，相当于人类罕见的外周性牙源性纤维瘤。另一种是棘皮瘤性龈瘤，似乎是成釉细胞瘤的一种形式，但与人类外周性成釉细胞瘤不同，它会侵犯骨组织；因此其生物学行为与人类骨内成釉细胞瘤相同。第三种是一种罕见病变，在兽医文献中被称为钙化上皮性牙源性肿瘤，尽管它并非人类钙化上皮性牙源性肿瘤的犬类对应物。有人建议用“产生淀粉样物质的牙源性肿瘤”这一术语来描述该病变。
