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用腔内锑电极测量的食管氧分压变化。

Variations in esophageal oxygen tension measured with intraluminal antimony electrodes.

作者信息

Tibbling L, Sjöberg F

机构信息

Department of Otorhinolaryngology, University Hospital, Linköping, Sweden.

出版信息

Dysphagia. 1995 Spring;10(2):121-5. doi: 10.1007/BF00440083.

DOI:10.1007/BF00440083
PMID:7600854
Abstract

Monocrystalline antimony electrodes (crystallographically oriented monocrystalline antimony; COMA) are known to be sensitive to oxygen and to pH. Accordingly, it has been shown that COMA electrodes can be used for the measurement of tissue oxygen tension provided the pH remains constant or is accounted for by the simultaneous use of a glass electrode. In this study the combination of a COMA together with a glass electrode was evaluated for measurement of esophageal oxygen tension in 5 patients. The COMA electrodes showed a mean value of 2.1 pH units higher than the glass electrodes, corresponding to a pO2 level in the esophagus of 10 kPa. As the more protracted oxygen effect on the COMA electrodes was easily recognized, especially in levels of the pH above 7.8 units, they were used for indirect evaluation of intraluminal oxygen tension in the esophagus in a further 57 patients, monitored over 24 h for gastroesophageal reflux disease. The intraluminal pO2 decreased in the supine position and with increase in age. An increase in pO2 was seen after eating and during reflux periods. The changes in pO2 are interpreted as being secondary to blood flow alterations in the esophagus.

摘要

单晶锑电极(晶体取向的单晶锑;COMA)已知对氧气和pH敏感。因此,已经表明,如果pH保持恒定或通过同时使用玻璃电极来考虑pH的影响,COMA电极可用于测量组织氧张力。在本研究中,评估了COMA与玻璃电极的组合用于测量5例患者的食管氧张力。COMA电极显示出比玻璃电极高2.1个pH单位的平均值,对应于食管中10 kPa的pO2水平。由于对COMA电极的氧效应更持久,很容易识别,尤其是在pH高于7.8单位时,在另外57例患有胃食管反流病且进行24小时监测的患者中,使用它们间接评估食管腔内氧张力。仰卧位时腔内pO2降低,且随着年龄增加而降低。进食后和反流期间可见pO2升高。pO2的变化被解释为食管血流改变的继发结果。

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引用本文的文献

1
New approach for elucidating the oxygen sensitivity and calibration of the antimony electrode.阐明锑电极氧敏感性及校准的新方法。
Med Biol Eng Comput. 1997 May;35(3):207-10. doi: 10.1007/BF02530039.

本文引用的文献

1
Computerized thermistor technique for indirect studies of esophageal blood flow.
Dysphagia. 1995 Spring;10(2):117-20. doi: 10.1007/BF00440082.
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Arterial oxygen tension in relation to age in healthy subjects.健康受试者动脉血氧分压与年龄的关系。
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Oesophageal reflux tests, manometry, endoscopy, biopsy, and radiology in healthy subjects.
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Accuracy and choice of procedures in 24-hour oesophageal pH monitoring with monocrystalline antimony electrodes.
Med Biol Eng Comput. 1986 Nov;24(6):602-8. doi: 10.1007/BF02446263.
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The oxygen sensitivity of a multipoint antimony electrode for tissue pH measurements. A study of the sensitivity for in vivo PO2 variations below 6 kPa.用于组织pH测量的多点锑电极的氧敏感性。对体内低于6 kPa的氧分压(PO2)变化的敏感性研究。
Scand J Clin Lab Invest. 1987 Feb;47(1):11-5. doi: 10.1080/00365518709168863.
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Microcirc Endothelium Lymphatics. 1990 Apr-Jun;6(2-3):127-48.