Shimizu S, Tada M, Kawai K
Department of Gastroenterology, Kyoto First Red Cross Hospital, Japan.
Endoscopy. 1995 Jan;27(1):27-31. doi: 10.1055/s-2007-1005628.
The present status of screening for gastric cancer, and the natural course of the disease, are the concerns of this paper. The development of new diagnostic modalities has led to an increase in the percentage of early gastric cancers detected. Improvements in technology, and alterations in nutrient intake, are linked to the reduction in the mortality from gastric cancer that has taken place. Observation of the natural course of gastric cancer development shows that "early gastric cancer" is genuinely the early stage of gastric cancer, and not a term for a different disease phenomenon. A "malignant cycle" was shown to be implicated in the process of cancer development.
本文关注的是胃癌筛查的现状以及该疾病的自然病程。新诊断方法的发展导致早期胃癌检出率有所提高。技术的进步以及营养摄入的改变与胃癌死亡率的降低相关。对胃癌发展自然病程的观察表明，“早期胃癌”确实是胃癌的早期阶段，而非不同疾病现象的术语。研究表明，癌症发展过程中存在“恶性周期”。
