Boocock P A, Roberts C A, Manchester K
Calvin Wells Laboratory, Department of Archaelogical Sciences, University of Bradford, UK.
Int J Lepr Other Mycobact Dis. 1995 Jun;63(2):265-8.
The maxillary sinuses of 133 skeletons from the medieval hospital of St. James and St. Mary Magdalene, Chichester, England, were analyzed for evidence of sinusitis. Of the sample, 16 individuals were considered to have suffered from lepromatous leprosy and 13 from tuberculoid leprosy. The most common bone change seen within the sinuses was the presence of new bone formation followed by pitting. Bone change was seen in 56.3% (9 of 16) of the individuals with lepromatous leprosy and 54.8% (57 of 104) of nonleprous individuals. These results are not statistically significant. Clinical evidence suggests that one should see a higher frequency in the lepromatous group. Possible explanations of this include environmental factors promoting the spread of droplet infection in an immunosuppressed community, in addition to which the small sample of leprous skeletons may bias the result.
对来自英国奇切斯特圣詹姆斯和抹大拉的圣玛丽中世纪医院的133具骨骼的上颌窦进行了分析，以寻找鼻窦炎的证据。在样本中，16人被认为患有瘤型麻风，13人患有结核样型麻风。鼻窦内最常见的骨质变化是新骨形成，其次是凹陷。在患有瘤型麻风的个体中，56.3%（16人中的9人）出现了骨质变化，在非麻风个体中，54.8%（104人中的57人）出现了骨质变化。这些结果无统计学意义。临床证据表明，瘤型组的发病率应该更高。对此的可能解释包括环境因素促进了免疫抑制人群中飞沫感染的传播，此外，麻风骨骼样本量小可能会使结果产生偏差。
