Matthews T W, Lampe H B, Dragosz K
Department of Otolaryngology, University of Western Ontario Faculty of Medicine.
J Otolaryngol. 1995 Apr;24(2):87-91.
The nutritional status of patients with head and neck cancer has been suspected as being a significant risk factor for surgical complications and cancer recurrence. Clinical dietary assessment was performed on a mixed group of 42 previously untreated, head and neck cancer patients scheduled to receive surgery with curative intent. Cox regression analysis was performed to investigate the relationship between demographic and tumour factors and nutritional status. Nutritional status correlated only with the locoregional stage of disease. A further regression analysis was performed to determine if nutritional status is an independent risk factor for early postoperative complications or recurrence. Nutritional status was not shown to influence surgical outcomes independent of tumour stage. Further study of the relationship between nutritional status and surgical results is required before recommending preoperative hyperalimentation in head and neck cancer patients.
头颈部癌症患者的营养状况被怀疑是手术并发症和癌症复发的重要风险因素。对一组42例计划接受根治性手术的未经治疗的头颈部癌症患者进行了临床饮食评估。进行Cox回归分析以研究人口统计学和肿瘤因素与营养状况之间的关系。营养状况仅与疾病的局部区域分期相关。进行了进一步的回归分析，以确定营养状况是否是术后早期并发症或复发的独立风险因素。结果表明，营养状况独立于肿瘤分期之外不会影响手术结果。在对头颈部癌症患者推荐术前胃肠外营养之前，需要进一步研究营养状况与手术结果之间的关系。
