与新加坡腹泻病相关的细菌、病毒、酵母和原生动物。
Bacteria, viruses, yeasts and protozoans associated with diarrheal disease in Singapore.
作者信息
Mendis L, Kumarasinghe G, Chow C, Liew H Y, Ramachandran N P, Jayawardene K, Thong K T, Howe J L, Lim E W, Zaman V
机构信息
Faculty of Medicine, University of Colombo, Sri Lanka.
出版信息
Pathology. 1995 Jan;27(1):48-52. doi: 10.1080/00313029500169452.
Labile toxin producing enterotoxic E. coli (ETEC) were the commonest pathogen isolated from diarrheal stools of hospitalized children (21%) and adults (26%) in Singapore. Salmonellas ranked a close second in children (19%). Other bacterial pathogens were isolated from less than 5% of subjects. Blastocystis hominis was detected in 4.3% of diarrheal stools when a simple sedimentation technique was used. Cryptosporidium was not detected at all. An analysis of yeast counts in smears of diarrheal and non-diarrheal stools suggested they were etiologically associated with at least 6% of diarrhea in children and 19% in adults. Testing for rotaviruses by Latex agglutination and for adenovirus by electronmicroscopy showed an association with 6 per cent and 3 per cent diarrhea respectively. The study highlighted a need for: case control studies on ETEC and B. hominis; studies on the epidemiology of diarrhea by yeasts; establishing the true incidence of adenovirus diarrhea; studies on the prevalence and seasonality of rotavirus infection in Singapore.
产不耐热毒素的肠毒素性大肠杆菌（ETEC）是从新加坡住院儿童（21%）和成人（26%）腹泻粪便中分离出的最常见病原体。沙门氏菌在儿童中排名第二（19%）。其他细菌病原体在不到5%的受试者中被分离出来。当使用简单沉淀技术时，在4.3%的腹泻粪便中检测到了人芽囊原虫。未检测到隐孢子虫。对腹泻和非腹泻粪便涂片的酵母计数分析表明，它们在病因上与儿童至少6%的腹泻和成人19%的腹泻有关。通过乳胶凝集试验检测轮状病毒，通过电子显微镜检测腺病毒，结果表明它们分别与6%和3%的腹泻有关。该研究强调需要：对ETEC和人芽囊原虫进行病例对照研究；对酵母引起腹泻的流行病学进行研究；确定腺病毒腹泻的真实发病率；对新加坡轮状病毒感染的患病率和季节性进行研究。
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