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无创血压估计技术的数学建模——第二部分:肱动脉血流动力学

Mathematical modeling of noninvasive blood pressure estimation techniques--Part II: Brachial hemodynamics.

作者信息

Ursino M, Cristalli C

机构信息

Department of Electronics, Computer Science and Systems, University of Bologna, Italy.

出版信息

J Biomech Eng. 1995 Feb;117(1):117-26. doi: 10.1115/1.2792259.

DOI:10.1115/1.2792259
PMID:7609475
Abstract

The main biomechanical factors which may affect the accuracy of the oscillometric method for indirect blood pressure measurement are analyzed using a new model of brachial hemodynamics. In a first stage of this work, the model has been used to reproduce some well-known responses of collapsing arteries, such as the sharp increase in compliance, and the nonlinear pressure-flow characteristic with negative dynamic resistance. In a second stage the model has been linked to the arm tissue mechanics description presented in a previous work. The final model so obtained has then been employed to analyze the pattern of the main hemodynamic quantities (pressure pulsations in the cuffs, blood volume changes, blood flow upstream and downstream of the cuffs) during deflation manoeuvres. The simulation results agree with those found in the recent literature quite well. Results indicate that the cuff pressure value for maximum pulsations exhibits a large plateau, located approximately around the mean arterial pressure. However, stiffness of wall artery, or stretching of the cuff internal surface, may significantly alter the obtained results causing a phenomena of "pseudo-hypertension."

摘要

使用一种新的肱动脉血流动力学模型,分析了可能影响示波法间接测量血压准确性的主要生物力学因素。在这项工作的第一阶段,该模型已被用于重现塌陷动脉的一些著名反应,如顺应性的急剧增加以及具有负动态阻力的非线性压力-流量特性。在第二阶段,该模型已与先前工作中提出的手臂组织力学描述相联系。然后,使用如此获得的最终模型来分析放气操作期间主要血流动力学量(袖带中的压力脉动、血容量变化、袖带上下游的血流)的模式。模拟结果与最近文献中的结果非常吻合。结果表明,最大脉动时的袖带压力值呈现出一个大的平台期,大约位于平均动脉压附近。然而,动脉壁的刚度或袖带内表面的拉伸可能会显著改变所获得的结果,导致“假性高血压”现象。

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