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[垂直传播导致新生儿丙型肝炎]

[Vertical transmission causing hepatitis C in a newborn infant].

作者信息

Grasselly M, Gagyi D, Schneider F, Oroszlán G

机构信息

Vas Megyei Markusovszky Kórház Csecsemö-és Gyermekosztálya, Fertözö Osztálya.

出版信息

Orv Hetil. 1995 Jul 2;136(27):1447-9.

PMID:7609972
Abstract

There is a case report of an intrauterine growth retarded infant who was suffering of sepsis caused by Klebsiella pneumoniae. An exchange transfusion was carried out because of hyperbilirubinaemia on the 5th day of life. 10 days later high bilirubin concentration was observed again parallel to the liver enzyme abnormalities. HCV-related antibodies were detectable in the sera of the newborn and his mother as well. The results of analysis of HCV RNA with the polymerase chain reaction in the infant and his mother suggest vertical transmission of HCV infection. This is the first case of HCV infection in the newborn caused by vertical transmission in Hungary.

摘要

有一份病例报告,一名宫内生长受限的婴儿患有由肺炎克雷伯菌引起的败血症。该婴儿在出生第5天因高胆红素血症接受了换血治疗。10天后,再次观察到高胆红素浓度,同时伴有肝酶异常。在新生儿及其母亲的血清中也可检测到丙型肝炎病毒(HCV)相关抗体。婴儿及其母亲的聚合酶链反应HCV RNA分析结果提示存在HCV感染的垂直传播。这是匈牙利首例因垂直传播导致新生儿感染HCV的病例。

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