van Erp A M, Kruk M R, Willekens-Bramer D C, Fermont P C, Nijsen M J
BFW/LACDR, Sylvius Laboratory, University of Leiden, The Netherlands.
Physiol Behav. 1995 May;57(5):887-92. doi: 10.1016/0031-9384(94)00335-3.
Electrical and chemical stimulation of specific parts of the paraventricular hypothalamus (PVH) and the adjacent hypothalamus induce self-grooming responses in the rat. The function of this hypothalamic grooming area (HGA) is not understood. The localization of the HGA in the hypothalamus suggests that grooming, a behavioural response to stressors, is somehow linked to the neuroendocrine response to stressors. In this study it is shown that grooming induced by the stressors, mild restraint and moistening of the fur of the rat, is not inhibited by complete, bilateral radiofrequency lesions of the HGA. The changes in grooming patterns observed following lesions suggest that the HGA may have a function in the timing of different grooming elements.
对大鼠室旁下丘脑（PVH）及相邻下丘脑的特定部位进行电刺激和化学刺激，可诱发大鼠的自我梳理反应。目前尚不清楚这个下丘脑梳理区域（HGA）的功能。HGA在下丘脑中的定位表明，梳理这一对应激源的行为反应，在某种程度上与对应激源的神经内分泌反应相关。本研究表明，由应激源（轻度束缚和弄湿大鼠毛发）诱发的梳理行为，不会因HGA的完全双侧射频损伤而受到抑制。损伤后观察到的梳理模式变化表明，HGA可能在不同梳理动作的时间安排上具有一定功能。
