Tianwu H, Watanabe Y, Asai M, Shimizu K, Takada S, Mizukoshi K
ENT Department, No. 1 Hospital of Xianyang City, Shaanxi, P. R. China.
Acta Otolaryngol Suppl. 1995;519:127-31. doi: 10.3109/00016489509121886.
In order to define the acute effects of a moderate quantity of alcohol on balance, related to the vestibular function, vestibulo-ocular reflex (VOR) test, caloric test and dynamic posturography (EquiTest) were performed. Ten healthy male volunteers aged 19-27 average 22.8) years old imbibed 1.5 ml whisky (alcohol content 43%) per kilogram of body weight within 5 min. Blood alcohol level (BAL) was measured before administration and then after 30, 90, and 150 min. Equilibrium examinations were performed immediately after each blood sample was taken. At the highest alcohol level, significant reductions were found in VOR gain, in the maximum slow-phase velocity of the caloric test and in the equilibrium score of the sensory organization test in condition 5, when compared with those before drinking. In some typical cases, the subjects' response in all tests were most disturbed at the time when the highest alcohol level was measured. From our results, we conclude that a moderate quantity of alcohol affects not only the oculomotor system but also the vestibular system. Furthermore, it was suggested that one of the reasons for postural instability after drinking alcohol may be reduced vestibular function.
为了确定适量酒精对与前庭功能相关的平衡的急性影响，进行了前庭眼反射（VOR）测试、冷热试验和动态姿势描记法（EquiTest）。10名年龄在19 - 27岁（平均22.8岁）的健康男性志愿者在5分钟内每公斤体重摄入1.5毫升威士忌（酒精含量43%）。在给药前以及给药后30、90和150分钟测量血液酒精水平（BAL）。每次采集血样后立即进行平衡检查。与饮酒前相比，在最高酒精水平时，发现VOR增益、冷热试验的最大慢相速度以及条件5下感觉组织试验的平衡分数显著降低。在一些典型案例中，在测量到最高酒精水平时，受试者在所有测试中的反应受到的干扰最大。根据我们的结果，我们得出结论，适量酒精不仅会影响动眼系统，还会影响前庭系统。此外，有人提出饮酒后姿势不稳的原因之一可能是前庭功能下降。
