Bentley D L
Imperial Cancer Research Fund, London, UK.
Curr Opin Genet Dev. 1995 Apr;5(2):210-6. doi: 10.1016/0959-437x(95)80010-7.
The process of transcription is a cycle of initiation, elongation and termination steps. Initiation and elongation can be rate-limiting for RNA synthesis, and recent evidence shows that transactivators can stimulate both these steps. A stable modification of the RNA polymerase II complex is probably required to convert it from a non-processive to a processive from.
转录过程是一个起始、延伸和终止步骤的循环。起始和延伸可能是RNA合成的限速步骤，最近的证据表明反式激活因子可以刺激这两个步骤。可能需要对RNA聚合酶II复合物进行稳定修饰，才能将其从非持续性形式转变为持续性形式。
