Malone D A, Dimeff R J, Lombardo J A, Sample R H
Department of Psychiatry and Psychology, Cleveland Clinic Foundation, Ohio 44195-5192, USA.
Clin J Sport Med. 1995;5(1):25-31. doi: 10.1097/00042752-199501000-00005.
The purpose of this study was to assess the psychiatric effects of anabolic-androgenic steroid (AAS) use and assess the frequency of other psychoactive substance use in a population of AAS users compared with non-AAS-using weight-lifter controls. One hundred sixty-four subjects were administered a demographic survey, including psychiatric history, substance use history, AAS use history, and medical history. Psychiatric diagnoses were made and psychological testing was performed. User categories were determined by history and urine testing. The user categories did not differ significantly on psychological testing. Past AAS users had a higher incidence of psychiatric diagnosis than the nonuser and current user groups. Hypomania was correlated with AAS use, and major depression with AAS discontinuation. Present psychoactive substance abuse or dependence was relatively low across all user categories. AAS dependence was seen in 12.9% of current users and 15.2% of past users of AAS. In conclusion, AAS use may lead to psychiatric disorders in certain individuals. Concurrent use of psychoactive drugs other than AAS does not appear to be common in intensively training weight lifters and bodybuilders.
本研究的目的是评估合成代谢雄激素类固醇（AAS）使用的精神影响，并评估与不使用AAS的举重运动员对照组相比，AAS使用者群体中使用其他精神活性物质的频率。164名受试者接受了一项人口统计学调查，包括精神病史、物质使用史、AAS使用史和病史。进行了精神科诊断并进行了心理测试。通过病史和尿液检测确定使用者类别。在心理测试中，使用者类别之间没有显著差异。既往AAS使用者的精神科诊断发生率高于非使用者和当前使用者组。轻躁狂与AAS使用相关，重度抑郁与AAS停用相关。在所有使用者类别中，目前精神活性物质滥用或依赖的情况相对较低。在当前AAS使用者中，12.9%存在AAS依赖，在既往AAS使用者中，15.2%存在AAS依赖。总之，使用AAS可能会导致某些个体出现精神障碍。在高强度训练的举重运动员和健美运动员中，同时使用AAS以外的精神活性药物似乎并不常见。
