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美国家庭肠外营养和肠内营养疗法的当前使用情况及临床结果。

Current use and clinical outcome of home parenteral and enteral nutrition therapies in the United States.

作者信息

Howard L, Ament M, Fleming C R, Shike M, Steiger E

机构信息

Department of Medicine, Albany Medical College, New York, USA.

出版信息

Gastroenterology. 1995 Aug;109(2):355-65. doi: 10.1016/0016-5085(95)90321-6.

Abstract

BACKGROUND & AIMS: Home nutrition support, especially when delivered parenterally, is very costly. The aim of this study is to examine current usage of home parenteral and enteral nutrition (HPEN) in the United States and the quality of therapy outcome.

METHODS

Medicare HPEN use from 1989 to 1992 was analyzed to assess use, growth, and costs. National Registry information collected on 9288 patients treated with HPEN from 1985 to 1992 was used to assess disease distribution and therapy outcome.

RESULTS

In the United States, there were approximately 40,000 parenteral and 152,000 enteral home patients in 1992. The usage of HPEN doubled between 1989 and 1992, and a large proportion was in patients with short survival. The prevalence of HPEN in the United States was 4-10 times higher than in other Western countries. Outcome data showed both therapies were relatively safe. The primary disease strongly influenced survival and rehabilitation, and age, per se, was not a reason to deny HPEN.

CONCLUSIONS

Predicted quality survival at home for several months, rather than a specific diagnosis, seems to be the soundest justification for HPEN. Its role in terminal conditions and patients without primary gastrointestinal diseases needs further evaluations.

摘要

背景与目的

家庭营养支持,尤其是肠外营养支持,费用高昂。本研究旨在调查美国目前家庭肠外和肠内营养(HPEN)的使用情况以及治疗效果质量。

方法

分析1989年至1992年医疗保险中HPEN的使用情况,以评估使用情况、增长情况和费用。利用1985年至1992年收集的9288例接受HPEN治疗患者的国家登记信息,评估疾病分布和治疗效果。

结果

1992年在美国,约有40000例接受肠外营养支持的家庭患者和152000例接受肠内营养支持的家庭患者。1989年至1992年期间,HPEN的使用量翻了一番,且很大一部分是生存期较短的患者。美国HPEN的患病率比其他西方国家高4至10倍。结果数据显示两种治疗方法相对安全。主要疾病对生存和康复有强烈影响,而年龄本身并非拒绝HPEN的理由。

结论

预计在家能有几个月的高质量生存期,而非特定诊断,似乎是HPEN最合理的依据。其在终末期疾病和无原发性胃肠道疾病患者中的作用需要进一步评估。

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