Reddy P, Malone M
Hartford Hospital, University of Connecticut, Storrs, USA.
JPEN J Parenter Enteral Nutr. 1998 Sep-Oct;22(5):302-10. doi: 10.1177/0148607198022005302.
Previous estimates of the cost of home parenteral and enteral nutrition (HPEN) have excluded hospitalization costs or were conducted abroad and have limited applicability in the United States. Few studies have used validated measures to determine the effect of home nutrition support on quality of life.
A cost and clinical outcome analysis was performed by retrospective review of charts of patients receiving HPEN from 1991 to 1996. Questionnaires to determine the influence of therapy on lifestyle (n = 41) and a general health status questionnaire, the short form 36-item survey (n = 39), were mailed to patients.
The annual cost per patient for parenteral solutions was $55,193 +/- 30,596 (mean +/- SD) based on Medicare charges and for enteral tube feedings was $9605 +/- 9327. The annual cost of hospitalization ranged from zero to $140,220 in the parenteral nutrition group and from zero to $39,204 in the enteral nutrition group. The annual number of hospitalizations per patient for patients receiving parenteral nutrition ranged from 0.52 to 1.10, compared with 0 to 0.50 in the enteral nutrition population. The health status of HPEN patients was significantly lower (p < .05) in five of the eight short-form 36 health domains compared with the general population. The areas of lifestyle most frequently affected were travel, sleep, exercise and leisure.
The majority of the cost of therapy was associated with the direct provision of nutrition, although in some patients the hospitalization expenditure exceeded this cost. Home nutrition support had a significant negative impact on a patient's quality of life and lifestyle.
以往对家庭肠外和肠内营养(HPEN)费用的估计未包括住院费用,或者是在国外进行的,在美国的适用性有限。很少有研究使用经过验证的方法来确定家庭营养支持对生活质量的影响。
通过回顾性查阅1991年至1996年接受HPEN治疗患者的病历进行成本和临床结果分析。向患者邮寄了用于确定治疗对生活方式影响的问卷(n = 41)以及一份一般健康状况问卷,即36项简短调查问卷(n = 39)。
根据医疗保险费用,肠外营养液每位患者的年费用为55,193美元±30,596美元(均值±标准差),肠内管饲喂养的年费用为9605美元±9327美元。肠外营养组的年住院费用从零到140,220美元不等,肠内营养组的年住院费用从零到39,204美元不等。接受肠外营养的患者每人每年的住院次数在0.52至1.10次之间,而肠内营养人群的住院次数为0至0.50次。与普通人群相比,HPEN患者在36项简短健康领域中的八项中有五项的健康状况显著较低(p < .05)。生活方式受影响最频繁的方面是旅行、睡眠、锻炼和休闲。
治疗费用的大部分与直接提供营养有关,尽管在一些患者中住院支出超过了这一费用。家庭营养支持对患者的生活质量和生活方式有显著的负面影响。