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人类毛小皮的原子力显微镜检查:环境对毛发形态影响的微观研究

Atomic force microscopy of human hair cuticles: a microscopic study of environmental effects on hair morphology.

作者信息

O'Connor S D, Komisarek K L, Baldeschwieler J D

机构信息

Division of Chemistry, California Institute of Technology, Pasadena, CA 91125, USA.

出版信息

J Invest Dermatol. 1995 Jul;105(1):96-9. doi: 10.1111/1523-1747.ep12313377.

DOI:10.1111/1523-1747.ep12313377
PMID:7615985
Abstract

We have used an atomic force microscope to provide quantitative real-time analysis of human hair morphologic changes under ambient conditions. This form of microscopy combines the lateral resolution of an electron microscope and the flexibility of a light microscope. Three experiments were performed: a study of hair morphology in air versus water, a kinetic study of hair hydration, and a determination of how pH changes affect hair morphology. The overlapping keratinized cells that form the hair cuticle spread out between 50 and 150% when hydrated, compared to a total shaft diameter change of 10%. This hydration reaches a saturation point within the first few minutes after immersion. Also, hair swells much more at higher pH.

摘要

我们使用原子力显微镜在环境条件下对人类头发的形态变化进行了定量实时分析。这种显微镜形式结合了电子显微镜的横向分辨率和光学显微镜的灵活性。进行了三个实验:一项关于头发在空气中与水中形态的研究、一项头发水合作用的动力学研究以及一项关于pH值变化如何影响头发形态的测定。与整个发干直径10%的变化相比,构成毛小皮的重叠角质化细胞在水合时会展开50%至150%。这种水合作用在浸入后的最初几分钟内达到饱和点。此外,头发在较高pH值下膨胀得更多。

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