Svensson B G, Nilsson A, Jonsson E, Schütz A, Akesson B, Hagmar L
Department of Occupational and Environmental Medicine, University Hospital, Lund, Sweden.
Scand J Work Environ Health. 1995 Apr;21(2):96-105. doi: 10.5271/sjweh.16.
This study assessed dietary habits and exposure to selenium, persistent organochlorine compounds, methylmercury, and methylamines among Swedish fishermen.
Two hundred and fifty randomly selected subjects from a cohort of 2896 fishermen from the Swedish east coast (Baltic Sea) and 8477 fishermen from the west coast (Skagerrak and Kattegatt) were interviewed along with 250 referents. Subgroups of fishermen and referents from different coastal areas were also selected for blood and urine sampling.
The interview data showed that fishermen ate almost twice as much fish as the 250 referents from the general population. The blood levels of mercury were twice as high, and the plasma selenium levels were 10-15% higher in the fishermen than in the referents. There was, however, no difference between the fishermen's cohorts with respect to these variables. Fishermen from the east coast ate more fatty fish than fishermen from the west coast, and they also had higher blood levels of persistent organochlorine compounds such as polychlorinated biphenyls and polychlorinated dibenzo p-dioxins and furans (present in fatty fish species in the Baltic Sea) than both the westcoast fishermen and the referents.
A cohort of Swedish eastcoast fishermen might be a suitable study base for epidemiologic studies on the mortality and cancer morbidity associated with dietary exposure to persistent organochlorine compounds.
本研究评估了瑞典渔民的饮食习惯以及他们对硒、持久性有机氯化合物、甲基汞和甲胺的暴露情况。
从瑞典东海岸（波罗的海）的2896名渔民队列和西海岸（斯卡格拉克海峡和卡特加特海峡）的8477名渔民队列中随机选取250名受试者，并选取250名对照者进行访谈。还从不同沿海地区的渔民和对照者亚组中采集血液和尿液样本。
访谈数据显示，渔民的鱼类摄入量几乎是来自普通人群的250名对照者的两倍。渔民的血液汞水平是对照者的两倍，血浆硒水平比对照者高10 - 15%。然而，在这些变量方面，渔民队列之间没有差异。东海岸的渔民比西海岸的渔民食用更多的高脂肪鱼类，并且他们血液中持久性有机氯化合物（如多氯联苯、多氯二苯并对二恶英和呋喃，存在于波罗的海的高脂肪鱼类中）的水平也高于西海岸渔民和对照者。
一群瑞典东海岸渔民可能是关于饮食暴露于持久性有机氯化合物相关死亡率和癌症发病率的流行病学研究的合适研究基础。
