Westaway J, Atkinson C M, Davies T, Petersen S A, Wailoo M P
Department of Child Health, University of Leicester.
Arch Dis Child. 1995 May;72(5):432-4. doi: 10.1136/adc.72.5.432.
Urinary cortisol excretion and rectal temperature were measured in 66 infants before and after immunisation against diphtheria, tetanus, pertussis, and Haemophilus influenzae type b. Immunisation produced a significant increase of rectal temperature the next night at all ages. Infants without an adult-like night time body temperature pattern had a significant increase in urinary cortisol excretion night and morning after immunisation. Once an adult-like night time body temperature pattern developed immunisation no longer significantly raised urinary cortisol output.
在66名婴儿接种白喉、破伤风、百日咳和b型流感嗜血杆菌疫苗前后，测量了他们的尿皮质醇排泄量和直肠温度。在所有年龄段，接种疫苗后的第二天晚上直肠温度均显著升高。没有类似成人夜间体温模式的婴儿在接种疫苗后的夜间和早晨尿皮质醇排泄量显著增加。一旦形成类似成人的夜间体温模式，接种疫苗就不再显著提高尿皮质醇的产量。
