Rawson D, Petersen S A, Wailoo M P
Department of Child Health, University of Leicester.
Arch Dis Child. 1990 Dec;65(12):1305-7. doi: 10.1136/adc.65.12.1305.
Continuous rectal temperature recordings were made from 32 babies the night after their first diphtheria, pertussis, and tetanus immunisation and compared with recordings made before immunisation. Tog values of clothes and wrapping and room temperatures were also recorded. We found that immunisation the day before disturbs the normal night time rhythm of deep body temperature. The rectal temperature of immunised babies was significantly higher than non-immunised babies from two hours into the night. We also found that there were considerable individual variations in the extent of disturbance of temperature rhythm. They were not correlated with thermal environment. There is no reason to suppose that these mild physiological responses to immunisation are in any way harmful.
对32名婴儿在首次接种白喉、百日咳和破伤风疫苗后的当晚进行直肠温度连续记录，并与接种疫苗前的记录进行比较。同时记录了衣物、包裹的热阻值以及室温。我们发现前一天的免疫接种会扰乱夜间深部体温的正常节律。从夜间两点起，接种疫苗婴儿的直肠温度显著高于未接种疫苗的婴儿。我们还发现，体温节律紊乱的程度存在相当大的个体差异。这些差异与热环境无关。没有理由认为这些对免疫接种的轻微生理反应会有任何危害。
