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基于“脊髓运动规则”的跑步机训练对脊髓损伤患者有效。

Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons.

作者信息

Wernig A, Müller S, Nanassy A, Cagol E

机构信息

Department of Physiology, University of Bonn, Germany.

出版信息

Eur J Neurosci. 1995 Apr 1;7(4):823-9. doi: 10.1111/j.1460-9568.1995.tb00686.x.

DOI:10.1111/j.1460-9568.1995.tb00686.x
PMID:7620630
Abstract

Rehabilitation of locomotion in spinal cord (s.c.) injured patients is unsatisfactory. Here we report the effects of a novel 'Laufband (LB; treadmill) therapy' based on 'rules of spinal locomotion' derived from lower vertebrates. Eighty-nine incompletely paralysed (44 chronic and 45 acute) para- and tetraplegics underwent this therapy, then were compared with 64 patients (24 chronic and 40 acute) treated conventionally. The programme consisted of daily upright walking on a motor driven LB initially with body weight support (BWS) provided by a harness and assisted limb movements by the therapists when necessary. Forty-four chronic patients with different degrees of paralysis undertook the programme for 3-20 weeks (median = 10.5), 0.5-18 years after s.c. damage. At the onset of LB therapy 33/44 patients were wheelchair-bound (no standing and/or walking without help by others) whereas at the end of therapy 25 patients (76%) had learned to walk independently, 7 patients with help [corrected]. Only 1 subject did not improve. It was striking that voluntary muscle activity in the resting position was still low in several patients who had gained walking capability. Eleven patients who could already walk before LB therapy improved in speed and endurance. Of the 44 patients, six were capable of staircase walking before LB therapy compared with 34 afterwards. In order to validate the apparent superiority of LB therapy two types of comparisons were performed. In a 'temporal' control 12 spastic paretic patients, still wheelchair-bound after the period of postacute conventional therapy, performed LB immediately thereafter. After completion of LB therapy nine of these patients had learned to walk without help from others.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

脊髓损伤患者的运动功能康复效果并不理想。在此,我们报告一种基于从低等脊椎动物得出的“脊髓运动规则”的新型“Laufband(LB;跑步机)疗法”的效果。89例不完全瘫痪(44例慢性和45例急性)的截瘫和四肢瘫患者接受了这种疗法,然后与64例接受传统治疗的患者(24例慢性和40例急性)进行比较。该方案包括最初在电动LB上每日直立行走,最初由吊带提供体重支持(BWS),必要时治疗师辅助肢体运动。44例不同程度瘫痪的慢性患者在脊髓损伤后0.5 - 18年接受该方案治疗3 - 20周(中位数 = 10.5周)。在LB治疗开始时,33/44例患者依赖轮椅(无法独立站立和/或行走),而在治疗结束时,25例患者(76%)学会了独立行走,7例患者需要帮助[已修正]。只有1例患者没有改善。令人惊讶的是,在一些已经获得行走能力的患者中,静息状态下的自主肌肉活动仍然很低。11例在LB治疗前就已经能够行走的患者在速度和耐力方面有所提高。在44例患者中,6例在LB治疗前能够上楼梯,而之后有34例能够上楼梯。为了验证LB疗法的明显优势,进行了两种类型的比较。在一个“时间”对照中,12例痉挛性轻瘫患者在急性后期传统治疗后仍依赖轮椅,随后立即进行LB治疗。在LB治疗完成后,这些患者中有9例学会了独立行走。(摘要截断于250字)

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