López Morante A, Sáez-Royuela F, Martín Lorente J L, Yuguero del Moral L, Ojeda Giménez C
Sección de Aparato Digestivo, Hospital General Yagüe, Burgos.
Gastroenterol Hepatol. 1995 Jan;18(1):7-10.
The prevalence of antibodies versus the hepatitis C virus (antiHCV) was studied in a group of 10 patients diagnosed with porphyria cutanea tarda (PCT) and the possible existence of subclinical forms of PCT was determined in 64 patients with chronic anti HCV positive liver diseases. The prevalence of anti HCV was found to be 40% in patients with PCT. In the group of patients with chronic anti HCV positive liver disease only one patient (1.5%) presented an increase in the urinary elimination of porphyrias in the absence of cutaneous lesions of photosensitivity. This study confirms the importance of the hepatitis C virus as a triggering agent of PCT. These results demonstrate the existence of a low prevalence of subclinical forms of PCT among patients with chronic anti HCV positive liver diseases.
在一组10例诊断为迟发性皮肤卟啉症（PCT）的患者中研究了丙型肝炎病毒抗体（抗-HCV）的流行情况，并在64例慢性抗-HCV阳性肝病患者中确定了PCT亚临床形式的可能存在。发现PCT患者中抗-HCV的流行率为40%。在慢性抗-HCV阳性肝病患者组中，只有1例患者（1.5%）在无光敏性皮肤病变的情况下出现卟啉尿排泄增加。本研究证实了丙型肝炎病毒作为PCT触发因素的重要性。这些结果表明，在慢性抗-HCV阳性肝病患者中，PCT亚临床形式的患病率较低。
