Liberman R P, Kopelowicz A
Community and Rehabilitative Psychiatry, West Los Angeles VA Medical Center, CA, USA.
Int Clin Psychopharmacol. 1995 Jan;9 Suppl 5:51-8. doi: 10.1097/00004850-199501005-00009.
The psychopathology and associated disabilities experienced by persons with schizophrenia have only partially responded to conventional pharmacological and psychosocial treatment approaches. Biobehavioral therapy employs behavioral and symptomatic assessment, social learning principles, and skills training, to amplify the effects of pharmacotherapy. Comprehensive, continuous, and integrated biobehavioral therapy--aiming at early detection and treatment of schizophrenic symptoms, family and social skills training, and teaching coping and illness self-management skills--has been documented to improve the course and outcome of schizophrenia as measured by symptom recurrence, social functioning, and quality of life. Biobehavioral therapies must be delivered in the context of a collaborative relationship among patients, families and clinicians that together can optimize outcomes. Services need to be provided by assertive, outreach, community-based teams that tailor the type, frequency and scope of services to the phase of the individual's illness.
精神分裂症患者所经历的精神病理学及相关残疾仅对传统的药物和心理社会治疗方法有部分反应。生物行为疗法采用行为和症状评估、社会学习原则及技能训练，以增强药物治疗的效果。全面、持续且综合的生物行为疗法——旨在早期发现和治疗精神分裂症症状、进行家庭和社交技能训练以及教授应对和疾病自我管理技能——已被证明可改善精神分裂症的病程和结局，这可通过症状复发、社会功能和生活质量来衡量。生物行为疗法必须在患者、家庭和临床医生之间的合作关系背景下实施，这样才能共同优化治疗效果。服务需要由积极主动、开展外展服务的社区团队提供，这些团队要根据个体疾病的阶段来调整服务的类型、频率和范围。
