阿尔茨海默型原发性退行性痴呆中的快速P2潜伏期延迟。

Flash P2 delay in primary degenerative dementia of the Alzheimer type.

Moore N C, Tucker K A, Jann M W, Hostetler R M, Coburn K L

Mercer University School of Medicine, Macon, Georgia, USA.

Prog Neuropsychopharmacol Biol Psychiatry. 1995 May;19(3):403-10. doi: 10.1016/0278-5846(95)00021-m.

Abstract

Flash visual evoked responses of 31 patients meeting DSM-III-R criteria for primary degenerative dementia of the Alzheimer type were compared with 31 healthy controls. 2. P1 latency was normal (75 +/- 6 msec Alzheimer's; 75 +/- 6 msec controls). 3. P2 was significantly delayed (162 +/- 32 msec, 147 +/- 20 msec, p < 0.03) among patients. 4. P1-P2 interpeak latency was significantly increased (87 +/- 32 msec, 71 +/- 21 msec, p < 0.03) among patients.

摘要

将31名符合《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）中阿尔茨海默型原发性退行性痴呆标准的患者的闪光视觉诱发电位与31名健康对照者进行比较。2. P1潜伏期正常（阿尔茨海默病患者为75±6毫秒；对照者为75±6毫秒）。3. 患者中P2明显延迟（分别为162±32毫秒、147±20毫秒，p<0.03）。4. 患者中P1-P2峰间潜伏期明显延长（分别为87±32毫秒、71±21毫秒，p<0.03）。