Hoyer-Ott M A, Reusch C, Minkus G
I. Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1995 Apr;23(2):155-61.
The affinity method has proved to be the first technique that succeeded in measuring feline GHb as it is not affected by structural differences of haemoglobin as traditional proceedings are. By its help the reference interval for feline GHb was established from blood samples of 62 healthy cats. It ranged between 0.31 to 1.58% with a median of 0.92%. 21 newly diagnosed diabetic cats were reliably determined to be diabetic, because the GHb exceeded significantly the upper limit of the reference interval of 1.30%. The statistical difference between diabetic and healthy cats was highly significant (p < 0.00001). It was confirmed that the GHb value helps to distinguish diabetic from transient hyperglycemic cats. Newly presented hyperglycemic cats suffer from diabetes mellitus, if their GHb values are increased (p < 0.00001).
亲和法已被证明是第一种成功测量猫糖化血红蛋白（GHb）的技术，因为它不像传统方法那样受血红蛋白结构差异的影响。借助该方法，从62只健康猫的血样中确定了猫GHb的参考区间。其范围在0.31%至1.58%之间，中位数为0.92%。21只新诊断的糖尿病猫被可靠地判定为患有糖尿病，因为它们的GHb显著超过了1.30%的参考区间上限。糖尿病猫和健康猫之间的统计学差异非常显著（p < 0.00001）。已证实GHb值有助于区分糖尿病猫和短暂性高血糖猫。如果新出现的高血糖猫的GHb值升高，则它们患有糖尿病（p < 0.00001）。
