城市垃圾焚烧厂工人血液中的二噁英浓度。

Dioxin concentrations in the blood of workers at municipal waste incinerators.

作者信息

Schecter A, Päpke O, Ball M, Lis A, Brandt-Rauf P

机构信息

Department of Preventive Medicine, State University of New York, Binghamton 13903, USA.

出版信息

Occup Environ Med. 1995 Jun;52(6):385-7. doi: 10.1136/oem.52.6.385.

DOI:10.1136/oem.52.6.385

PMID:7627315

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1128242/

Abstract

OBJECTIVES

Increased concentrations of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-furans (PCDFs) in pooled blood samples from workers at municipal waste incinerators have been reported. This study was undertaken to confirm these results in individual blood samples from potentially exposed and unexposed workers at municipal waste incinerators compared with matched unexposed controls and compared with concentrations in the slag and fly ash from the municipal waste incinerators.

METHODS

Concentrations of PCDDs and PCDFs were determined in the blood of 10 workers from an old municipal waste incinerator without adequate pollution controls, 11 workers from a newer incinerator with modern pollution controls, and 25 controls from the general population group matched for age (+/- 10 years), sex, and race, and in the slag and fly ash from the older incinerator.

RESULTS

Significant increases of certain PCDDs and PCDFs were found in the blood of the workers from the older incinerator compared with the controls as follows: octaCDD (1051 (438) v 637 (344), P < 0.001), hexaCDF (52.3 (28.7) v 30.2 (18.2), P < 0.01), heptaCDF (43.9 (30.4) v 22.7 (12.4), P < 0.001), total PCDDs (1262 (484) v 825 (454), P < 0.001), total PCDFs (133.0 (68.1) v 93.7 (36.7), P < 0.05), and total PCDD/Fs (1395 (537) v 918 (437), P < 0.001). The workers from the older incinerator with the greatest exposure were found to have the most significant increases of the blood PCDDs and PCDFs, and the pattern of increased PCDD and PCDF congeners in the blood corresponded to the pattern in the incinerator slag and ash. No significant differences were found between the blood concentrations of the workers at the newer incinerator and the controls.

CONCLUSION

Occupational exposure to slag and fly ash from municipal waste incinerators may increase the blood concentrations of PCDDs and PCDFs. Modern pollution control technology in new incinerators may be able to minimise potential exposure to slag and fly ash and thus the absorption of PCDDs and PCDFs from this source.

摘要

目的

有报告称，城市垃圾焚烧厂工人的混合血样中多氯二苯并对二噁英（PCDDs）和多氯二苯并呋喃（PCDFs）的浓度有所增加。本研究旨在通过比较城市垃圾焚烧厂潜在暴露和未暴露工人的个体血样与匹配的未暴露对照，并与城市垃圾焚烧厂的炉渣和飞灰中的浓度进行比较，来证实这些结果。

方法

测定了来自一家没有适当污染控制措施的旧城市垃圾焚烧厂的10名工人、一家有现代污染控制措施的新焚烧厂的11名工人以及从普通人群中匹配的年龄（±10岁）、性别和种族的25名对照的血液中PCDDs和PCDFs的浓度，以及旧焚烧厂的炉渣和飞灰中的浓度。

结果

与对照组相比，旧焚烧厂工人血液中某些PCDDs和PCDFs显著增加，如下所示：八氯二苯并对二噁英（1051（438）对637（344），P<0.001）、六氯二苯并呋喃（52.3（28.7）对30.2（18.2），P<0.01）、七氯二苯并呋喃（43.9（30.4）对22.7（12.4），P<0.001）、总PCDDs（1262（484）对825（454），P<0.001）、总PCDFs（133.0（68.1）对93.7（36.），P<0.05）以及总PCDD/Fs（1395（537）对918（437），P<0.001）。发现暴露程度最高的旧焚烧厂工人血液中PCDDs和PCDFs增加最为显著，血液中PCDD和PCDF同系物增加的模式与焚烧炉炉渣和飞灰中的模式一致。新焚烧厂工人的血液浓度与对照组之间未发现显著差异。