Sabbah P, Simond G, Levrier O, Habib M, Trabaud V, Murayama N, Mazoyer B M, Briant J F, Raybaud C, Salamon G
Department of Neuroradiology, Hospital La Timone, France.
Eur Neurol. 1995;35(3):131-6. doi: 10.1159/000117108.
Functional activations of the human brain cortex were observed with a standard 1.5-tesla MR imaging system using a long time echo fast low-angle shot sequence. Neural activation increases regional cerebral blood flow resulting in increased capillaries and venous blood oxygenation. Processing requires adapted algorithms because the time course of intensity signal showed fluctuations of the baseline. The use of a 'follow-up' method to generate activation maps is proposed. Brain activation was detected in striate cortex during photic stimulation and in sensorimotor areas while subjects were moving their hands. In mental imagery tasks, we observed a primary and secondary visual cortex activation during memory recall of the flashing light. Motor ideation showed an activation of the rolandic areas.
使用标准的1.5特斯拉磁共振成像系统,采用长回波快速低角度激发序列,观察了人类大脑皮层的功能激活情况。神经激活会增加局部脑血流量,从而导致毛细血管和静脉血氧合增加。由于强度信号的时间进程显示出基线波动,因此处理需要采用适应性算法。建议使用“后续”方法来生成激活图。在光刺激期间,纹状皮层检测到脑激活,而在受试者移动手部时,感觉运动区检测到脑激活。在心理意象任务中,我们观察到在对闪烁光的记忆回忆过程中,初级和次级视觉皮层激活。运动意念显示罗兰区激活。