Nyberg G, Andersson J, Antoni G, Lilja A, Pellettieri L, Valind S, Långström B
Department of Neurosurgery, University Hospital, Uppsala, Sweden.
Acta Neurochir (Wien). 1996;138(6):684-94. doi: 10.1007/BF01411473.
Treatment of tumours and vascular lesions in or close to eloquent cortex may inflict neurological deficits. Intra-operative mapping procedures have been used for many decades in efforts to minimize neurological sequelae. The possibility for non-invasive pre-operative brain mapping has emerged with the advent of positron emission tomography (PET). In this paper we report on 11 patients with a tumour or vascular lesion in or close to the sensorimotor (10 patients) or visual cortex (one patient). The patients were subjected to activation PET scanning by means of vibrotactile or visual stimulation. The results show that in most of the patients the important relation between the lesion and the sensorimotor cortex could be determined. The patient with a lesion in the occipital lobe had involvement of the entire visual cortex as judged by comparison with activated areas on the nonlesion side.
治疗位于明确功能区皮质内或其附近的肿瘤和血管病变可能会导致神经功能缺损。数十年来，术中定位程序一直被用于尽量减少神经后遗症。随着正电子发射断层扫描（PET）的出现，术前非侵入性脑图谱绘制成为可能。在本文中，我们报告了11例肿瘤或血管病变位于感觉运动区（10例）或视觉皮质（1例）内或其附近的患者。通过振动触觉或视觉刺激对这些患者进行了PET激活扫描。结果表明，在大多数患者中，可以确定病变与感觉运动皮质之间的重要关系。通过与非病变侧的激活区域进行比较判断，枕叶有病变的患者整个视觉皮质均受累。
