Papadopoulos K I, Jönsson A, Berntorp E, Törnquist C, Hulthén U L
Department of Endocrinology, Lund University Clinics, General Hospital, Malmö, Sweden.
J Intern Med. 1995 Aug;238(2):175-8. doi: 10.1111/j.1365-2796.1995.tb00916.x.
A 51-year-old Caucasian male without previous history of thromboembolic disease developed Coomb's positive haemolytic anaemia, thrombocytopenia, transient paranoid psychosis and bilateral adrenal haemorrhage with primary adrenal failure after surgery for inguinal hernia. The activated partial thromboplastin time was spontaneously prolonged, and lupus anticoagulant and anticardiolipin antibodies were detected. In the absence of criteria for classification of systemic lupus erythematosus (SLE), the entity was classified as a primary antiphospholipid syndrome. Despite the persistence of the serological abnormalities, the patient remains well after substitution with cortisone. Primary adrenal failure due to adrenal haemorrhage can be associated with the primary antiphospholipid syndrome.
一名51岁无血栓栓塞疾病史的白种男性，在腹股沟疝手术后出现库姆斯试验阳性的溶血性贫血、血小板减少、短暂性偏执型精神病以及双侧肾上腺出血伴原发性肾上腺功能不全。活化部分凝血活酶时间自发延长，检测到狼疮抗凝物和抗心磷脂抗体。由于缺乏系统性红斑狼疮（SLE）的分类标准，该病例被归类为原发性抗磷脂综合征。尽管血清学异常持续存在，但患者在使用可的松替代治疗后情况良好。肾上腺出血导致的原发性肾上腺功能不全可能与原发性抗磷脂综合征相关。
