环境流行病学中化学物质暴露生物标志物使用的有效性标准。

Validity criteria for the use of biological markers of exposure to chemical agents in environmental epidemiology.

作者信息

Schulte P A, Talaska G

机构信息

Screening and Notification Section, National Institute for Occupational Safety and Health, CDC, Cincinnati, OH 45226, USA.

出版信息

Toxicology. 1995 Jul 26;101(1-2):73-88. doi: 10.1016/0300-483x(95)03020-g.

DOI:10.1016/0300-483x(95)03020-g

PMID:7631325

Abstract

Biomarkers may prove very useful in increasing the precision of exposure estimates during field epidemiological studies of environmental and occupational exposures. However, the determination of validity of exposure biomarkers is a laborious process. It is also a process that needs collaboration between laboratory and field scientists if biological markers of exposure are to be useful tools in environmental epidemiology.

摘要

在环境与职业暴露的现场流行病学研究中，生物标志物可能在提高暴露估计的精确度方面非常有用。然而，确定暴露生物标志物的有效性是一个费力的过程。如果暴露生物标志物要成为环境流行病学中的有用工具，这也是一个需要实验室科学家和现场科学家合作的过程。