Jonsson M, Karlsson R, Rylander E, Bodén E, Edlund K, Evander M, Gustavsson A, Wadell G
Department of Family Medicine, University of Umeå, Sweden.
Genitourin Med. 1995 Jun;71(3):158-62. doi: 10.1136/sti.71.3.158.
To assess the prevalence of lower genital tract symptoms and the association between reported symptoms and past and present signs of sexually transmitted diseases (STD) in young women.
All women belonging to the 19-, 21-, 23- and 25-year age cohorts and living in the catchment area of the community health centre, were invited by mail to take part in a population-based study. The participants answered a structured questionnaire and a gynaecologic examination was performed. Samples for wet smear, cervical Pap smear, HPV DNA determination and Chlamydia trachomatis culture were taken at the gynaecologic examination. The presence of genital warts was noted. A blood sample was analysed for antibodies against C trachomatis and HSV-2.
The community health care centre was located in Umeå, a city in Northern Sweden.
Of the 886 women who were eligible, 611 (70%) participated in the investigation. One out of four women reported symptoms from the lower genital tract. The most commonly reported symptoms were itching, followed by discharge, and soreness. The most commonly reported STD was C trachomatis (15%). The most prevalent present STD was HPV infection (20%) whereas C trachomatis infection could be isolated from 2.7% of the women. Antibodies against C trachomatis and HSV-2 were present among 22% and 6% of the women, respectively. There was a significant correlation between the women's complaint of vaginal discharge and previous C trachomatis infection, lack of lactobacilli and presence of leucocytosis in wet smear.
We have in a population-based study of young healthy women found that one out of four women had some kind of lower genital tract complaint. Itching was the most commonly reported symptom and was associated with pseudohyphae and acetowhite patches. Reported vaginal discharge and soreness were associated with the history of a past C trachomatis infection and signs of a disturbed vaginal flora.
评估年轻女性下生殖道症状的患病率，以及所报告症状与既往和当前性传播疾病（STD）体征之间的关联。
邀请所有年龄在19、21、23和25岁，居住在社区卫生中心服务区域内的女性通过邮件参与一项基于人群的研究。参与者回答一份结构化问卷，并接受妇科检查。在妇科检查时采集湿涂片、宫颈巴氏涂片、HPV DNA检测和沙眼衣原体培养的样本。记录尖锐湿疣的存在情况。采集血样分析抗沙眼衣原体和HSV-2的抗体。
社区医疗中心位于瑞典北部城市于默奥。
在886名符合条件的女性中，611名（70%）参与了调查。四分之一的女性报告有下生殖道症状。最常报告的症状是瘙痒，其次是分泌物增多和疼痛。最常报告的性传播疾病是沙眼衣原体（15%）。当前最普遍的性传播疾病是HPV感染（20%），而2.7%的女性可分离出沙眼衣原体感染。分别有22%和6%的女性存在抗沙眼衣原体和HSV-2的抗体。女性阴道分泌物增多的主诉与既往沙眼衣原体感染、湿涂片中缺乏乳酸杆菌和存在白细胞增多之间存在显著相关性。
在一项针对年轻健康女性的基于人群的研究中，我们发现四分之一的女性有某种下生殖道不适。瘙痒是最常报告的症状，且与假菌丝和醋酸白班有关。报告的阴道分泌物增多和疼痛与既往沙眼衣原体感染史及阴道菌群紊乱的体征有关。
