Daoud M S, Rogers R S
Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA.
Semin Dermatol. 1995 Jun;14(2):135-9. doi: 10.1016/s1085-5629(05)80009-4.
Melkersson-Rosenthal syndrome is a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue. However, the classic triad is not frequently seen in its complete form. Monosymptomatic and oligosymptomatic forms are more common. The histological findings of sarcoid-like granuloma in skin or mucosal biopsy specimens support the diagnosis. The course is chronic but benign. Treatment is difficult, but intralesional or systemic corticosteroids may be helpful.
梅尔克森-罗森塔尔综合征的特征为复发性口面部肿胀、复发性面瘫和沟纹舌三联征。然而,典型的三联征完整形式并不常见。单症状和少症状形式更为常见。皮肤或黏膜活检标本中出现类肉瘤样肉芽肿的组织学表现支持该诊断。病程呈慢性,但为良性。治疗困难,但病灶内或全身应用皮质类固醇可能有效。