St John K R, Zardiackas L D, Terry R C, Teasdall R D, Cooke S E, Mitias H M
University of Mississippi Medical Center, Jackson 39216, USA.
J Appl Biomater. 1995 Summer;6(2):89-97. doi: 10.1002/jab.770060202.
A synthetic composite bone graft material, composed of fibrillar collagen, hydroxyapatite, and tricalcium phosphate, was evaluated in canine femoral shaft defects and compared to ungrafted defects and defects grafted with autogenous bone. The results of mechanical testing of the grafted femora in torsion at 1 year postoperatively were previously reported. This report details the histological and microscopic features of the graft sites. The results of this study suggest that the healing of the graft site is not yet complete at 1 year and that healing may be more complete in defects that received the synthetic graft as compared to ungrafted sites and autogenous bone graft. The bone tissue appears to respond to the graft particles as if they were bone particles.
一种由纤维状胶原蛋白、羟基磷灰石和磷酸三钙组成的合成复合骨移植材料，在犬股骨干缺损中进行了评估，并与未移植的缺损以及自体骨移植的缺损进行了比较。先前已报道了术后1年移植股骨扭转力学测试的结果。本报告详细描述了移植部位的组织学和微观特征。这项研究的结果表明，移植部位在1年时愈合尚未完成，与未移植部位和自体骨移植相比，接受合成移植的缺损部位愈合可能更完全。骨组织似乎对移植颗粒产生反应，就好像它们是骨颗粒一样。
