Zardiackas L D, Teasdall R D, Black R J, Jones G S, St John K R, Dillon L D, Hughes J L
Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson 39216, USA.
J Appl Biomater. 1994 Winter;5(4):277-83. doi: 10.1002/jab.770050402.
The need for alternatives to autogenous bone grafts is widely recognized. This study compared the torsional strength of canine femora 1 year after grafting with one of three forms of a collagen/hydroxyapatite/tricalcium phosphate bone grafting material (COLLAGRAFTTM), autogenous bone, or no graft. The groups were compared to each other and to the unoperated contralateral femora. Results of torsional testing were evaluated for torsional strength, torsional displacement, total energy to fracture and White fracture mode. Data analysis showed lower torsional strength of the operated vs. unoperated femora with the exception of morsellized COLLAGRAFTTM material, which had higher strength. However, the only difference in the operated groups was that the morsellized COLLAGRAFTTM had greater strength than several groups including the autogenous bone group. There was no difference found in angular displacement between any of the groups. However, there was a difference in the energy to fracture in both strip forms of the COLLAGRAFTTM. The final conclusion is that in this model, grafting with COLLAGRAFTTM provided torsional properties at one year postoperatively at least equivalent to autogenous bone.
自体骨移植替代物的需求已得到广泛认可。本研究比较了犬股骨在移植三种形式的胶原/羟基磷灰石/磷酸三钙骨移植材料（COLLAGRAFTTM）之一、自体骨或不进行移植后1年的抗扭强度。将这些组相互比较，并与未手术的对侧股骨进行比较。对扭转测试结果评估了抗扭强度、扭转位移、骨折总能量和骨折模式。数据分析表明，除了颗粒状COLLAGRAFTTM材料强度较高外，手术侧股骨的抗扭强度低于未手术侧。然而，手术组之间唯一的差异是颗粒状COLLAGRAFTTM的强度高于包括自体骨组在内的几个组。各实验组之间在角位移方面未发现差异。然而，两种条状COLLAGRAFTTM在骨折能量方面存在差异。最终结论是，在该模型中，使用COLLAGRAFTTM移植在术后一年提供的扭转特性至少与自体骨相当。
