Kitamura K, Yasuoka R, Ohara M, Shimotsuma M, Hagiwara A, Yamane T, Yamaguchi T, Takahashi T
First Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
Surg Today. 1995;25(5):433-5. doi: 10.1007/BF00311821.
We report herein the unusual case of a 55-year-old woman who developed a severe systemic allergy to Avitene (microfibrillar collagen hydrochloride), a xenogeneic agent sometimes used for topical hemostasis in laparoscopic cholecystectomy. The patient developed fever, general fatigue, mild liver dysfunction, and prominent eosinophilia postoperatively. A skin allergy test confirmed that these abnormal findings were attributable to an allergic reaction to Avitene.
我们在此报告一例罕见病例，一名55岁女性对Avitene（微纤维胶原盐酸盐）产生了严重的全身过敏反应，Avitene是一种有时用于腹腔镜胆囊切除术局部止血的异种制剂。患者术后出现发热、全身乏力、轻度肝功能障碍和明显的嗜酸性粒细胞增多。皮肤过敏试验证实这些异常发现归因于对Avitene的过敏反应。
