Vein A, Voznesenskaya T, Danilov A
Department of Neurology, Sechenov's Moscow Medical Academy, Russia.
Cephalalgia. 1995 Apr;15(2):129-31; discussion 78. doi: 10.1046/j.1468-2982.1995.015002129.x.
The effects of aspirin on the contingent negative variation (CNV) of 16 healthy, right-handed volunteers were studied in accordance with a placebo-controlled double-blind crossover design. Early and late CNV factors were measured. Aspirin caused a statistically significant decrease of the early wave and an increase of mean amplitude of the late wave. A central action of aspirin, affecting noradrenergic and dopaminergic structures, may be responsible for the CNV changes.
按照安慰剂对照双盲交叉设计,研究了阿司匹林对16名健康右利手志愿者的关联负变化(CNV)的影响。测量了早期和晚期CNV因子。阿司匹林使早期波在统计学上显著降低,晚期波平均振幅增加。阿司匹林影响去甲肾上腺素能和多巴胺能结构的中枢作用可能是CNV变化的原因。