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一名患有褐黄病的58岁女性出现了类似于强直性脊柱炎的脊柱异常。

Spinal abnormalities similar to ankylosing spondylitis in a 58-year-old woman with ochronosis.

作者信息

Kabasakal Y, Kiyici I, Ozmen D, Yagci A, Gumusdis G

机构信息

Department of Rheumatology, Ege University Medical School, Izmir, Turkey.

出版信息

Clin Rheumatol. 1995 May;14(3):355-7. doi: 10.1007/BF02208354.

DOI:10.1007/BF02208354
PMID:7641516
Abstract

Ochronotic arthropathy (spondylosis or peripheral arthropathy) is a late complication of alkaptonuria. There is a tendency for HLA-B27 positive patients with alkaptonuria to develop ochronotic spondylosis. A 58-year-old white woman, presented with ochronotic spondylosis. She was HLA-B27 positive. Her family history was positive for alkaptonuria. Ochronotic patients with HLA-B27 positivity develop spinal changes similar to ankylosing spondylitis (AS).

摘要

褐黄病性关节病（脊柱炎或外周关节病）是尿黑酸尿症的晚期并发症。HLA - B27阳性的尿黑酸尿症患者有发生褐黄病性脊柱炎的倾向。一名58岁的白人女性，患有褐黄病性脊柱炎。她HLA - B27阳性。她的家族史中有尿黑酸尿症阳性。HLA - B27阳性的褐黄病患者会出现与强直性脊柱炎（AS）相似的脊柱改变。

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Clin Rheumatol. 1995 May;14(3):355-7. doi: 10.1007/BF02208354.
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本文引用的文献

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Behçet's disease: lack of correlation of clinical manifestations with HLA antigens.白塞病：临床表现与人类白细胞抗原（HLA）抗原之间缺乏相关性。
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Ochronotic spondyloarthropathy: spinal involvement resembling ankylosing spondylitis.褐黄病性脊椎关节病：脊柱受累类似于强直性脊柱炎。
Clin Rheumatol. 2006 Jul;25(4):598-601. doi: 10.1007/s10067-005-0038-8. Epub 2005 Nov 3.
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Alkaptonuric ochronosis with aortic valve and joint replacements and femoral fracture: a case report and literature review.伴主动脉瓣置换、关节置换及股骨骨折的尿黑酸尿性褐黄病：一例报告及文献复习
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The coexistence of ochronosis and ankylosing spondylitis.褐黄病与强直性脊柱炎共存。
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The coexistence of ochronosis and ankylosing spondylitis.褐黄病与强直性脊柱炎共存。
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HLA antigens and alkaptonuria.人类白细胞抗原（HLA）抗原与黑尿症
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