Crouch A C, Baxby D, McCracken C M, Gaskell R M, Bennett M
Department of Medical Microbiology, University of Liverpool, UK.
Epidemiol Infect. 1995 Aug;115(1):185-91. doi: 10.1017/s0950268800058258.
The reservoir host of cowpox virus in Western Europe is not known, but epidemiological evidence from human and feline infections indicates that the virus is probably endemic in small wild rodents. Therefore, serum and tissue samples were collected from a variety of wild British mammals and some birds, and tested for evidence of Orthopoxvirus infection. Antibody reacting with cowpox virus was detected in 9/44 (20%) bank voles (Clethrionomys glareolus), 8/24 (33%) field voles (Microtus agrestis), 17/86 (20%) wood mice (Apodemus sylvaticus) and 1/44 house mice (Mus musculus), but in no other animal species tested. Although virus was not isolated from any animal, this serological survey, together with other evidence, suggests that bank and field voles and wood mice are the main reservoir hosts of cowpox virus in Great Britain.
西欧痘苗病毒的储存宿主尚不清楚,但来自人类和猫科动物感染的流行病学证据表明,该病毒可能在小型野生啮齿动物中呈地方性流行。因此,从英国的各种野生哺乳动物和一些鸟类中采集了血清和组织样本,并检测是否有正痘病毒感染的证据。在9/44(20%)的棕背䶄(Clethrionomys glareolus)、8/24(33%)的田鼠(Microtus agrestis)、17/86(20%)的林姬鼠(Apodemus sylvaticus)和1/44的家鼠(Mus musculus)中检测到了与痘苗病毒反应的抗体,但在其他受试动物物种中未检测到。尽管未从任何动物中分离出病毒,但这项血清学调查以及其他证据表明,棕背䶄、田鼠和林姬鼠是英国痘苗病毒的主要储存宿主。