Grzybek Maciej, Tołkacz Katarzyna, Sironen Tarja, Mäki Sanna, Alsarraf Mohammed, Behnke-Borowczyk Jolanta, Biernat Beata, Nowicka Joanna, Vaheri Antti, Henttonen Heikki, Behnke Jerzy M, Bajer Anna
Department of Tropical Parasitology, Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Powstania Styczniowego 9B, 81-519 Gdynia, Poland.
Department of Eco-Epidemiology for Parasitic Diseases, Faculty of Biology, University of Warsaw, 1 Miecznikowa Str, 02-096 Warsaw, Poland.
Animals (Basel). 2020 Oct 6;10(10):1820. doi: 10.3390/ani10101820.
Rodents are known to be reservoir hosts for a plethora of zoonotic viruses and therefore play a significant role in the dissemination of these pathogens. We trapped three vole species ( and ) in northeastern Poland, all of which are widely distributed species in Europe. Using immunofluorescence assays, we assessed serum samples for the presence of antibodies to hantaviruses, arenaviruses and cowpox viruses (CPXV). We detected antibodies against CPXV and Puumala hantavirus (PUUV), the overall seroprevalence of combined viral infections being 18.2% [10.5-29.3] and mostly attributed to CPXV. We detected only one PUUV/TULV cross-reaction in (1.3% [0.1-7.9]), but found similar levels of antibodies against CPXV in all three vole species. There were no significant differences in seroprevalence of CPXV among host species and age categories, nor between the sexes. These results contribute to our understanding of the distribution and abundance of CPXV in voles in Europe, and confirm that CPXV circulates also in and voles in northeastern Poland.
已知啮齿动物是多种人畜共患病毒的宿主，因此在这些病原体的传播中发挥着重要作用。我们在波兰东北部捕获了三种田鼠（和），它们都是在欧洲广泛分布的物种。我们使用免疫荧光测定法，评估血清样本中是否存在针对汉坦病毒、沙粒病毒和牛痘病毒（CPXV）的抗体。我们检测到了针对CPXV和普马拉汉坦病毒（PUUV）的抗体，病毒混合感染的总体血清阳性率为18.2%[10.5-29.3]，且大多归因于CPXV。我们仅在（1.3%[0.1-7.9]）中检测到一例PUUV/TULV交叉反应，但在所有三种田鼠物种中发现了相似水平的针对CPXV的抗体。宿主物种和年龄类别之间以及性别之间，CPXV的血清阳性率均无显著差异。这些结果有助于我们了解欧洲田鼠中CPXV的分布和丰度，并证实CPXV也在波兰东北部的和田鼠中传播。
