一名戈谢病患者的抗硫脂抗体与神经病变
Antisulfatide antibody and neuropathy in a patient with Gaucher's disease.
作者信息
McAlarney T, Pastores G M, Hays A P, Latov N
机构信息
Department of Neurology, College of Physicians & Surgeons of Columbia University, New York, NY, USA.
出版信息
Neurology. 1995 Aug;45(8):1622-3. doi: 10.1212/wnl.45.8.1622.
PMID:7644066
Abstract
We report the presence of antisulfatide antibodies in a patient with type I Gaucher's disease and peripheral neuropathy. The association of Gaucher's disease with hypergammaglobulinemia and monoclonal gammopathy is well documented whereas its association with peripheral neuropathy is rare. We discuss whether antibodies directed against the sulfatide antigen are related to Gaucher's disease or are a coincidental association.
摘要
我们报告了一名患有I型戈谢病和周围神经病变的患者体内存在抗硫脂抗体。戈谢病与高球蛋白血症和单克隆丙种球蛋白病的关联已有充分记载，而其与周围神经病变的关联则较为罕见。我们讨论了针对硫脂抗原的抗体是与戈谢病相关，还是一种偶然的关联。
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