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职业接触低浓度二硫化碳(CS₂)工人健康状况评估。第二部分:中枢神经系统(CNS)检查的综合方法。

The evaluation of the health state of the workers occupationally exposed to low concentration of carbon disulphide (CS2). Part two: The complex way of the examination of the central nervous system (CNS).

作者信息

Chrostek Maj J, Czeczótko B

机构信息

Department of Toxicology Collegium Medicum, Jagiellonian University, Kraków, Poland.

出版信息

Przegl Lek. 1995;52(5):252-6.

PMID:7644690
Abstract

The results of evaluation of health state of CNS of 114 healthy workers occupationally exposed to CS2 were demonstrated. The concentration of CS2 in the air was 0-65 mg/m3. 62 people from the control group underwent an examination in the same way--before employment and after 5 years. Psychiatric examination, psychological organic tests (Bender, Graham Kendall, Benton) and EEG record were performed. The examination results were evaluated separately and together by means of arbitrary scale of pathological changes which constituted a complex evaluation of CNS. A considerable deterioration of CNS was stated which was reflection of pathological changes of a functional type. After 5 years this complex way of evaluation of CNS in exposed workers significantly more pathological changes was evidenced then ones in the control group. In 20 exposed men who obtained the worst results in the evaluation of CNS, the head computer tomography was performed. In 60% mentioned people cortical and/or subcortical atrophy was found, described in most people to be small. At the same time it is important to state that mentioned CNS examination enables an early evaluation of functional and morphological state of CNS in people who are occupationally exposed to low concentration of CS2.

摘要

展示了114名职业性接触二硫化碳的健康工人中枢神经系统健康状况的评估结果。空气中二硫化碳的浓度为0至65毫克/立方米。对照组的62人以同样的方式进行了检查——就业前和5年后。进行了精神病学检查、心理器质性测试(本德尔、格雷厄姆·肯德尔、本顿测试)和脑电图记录。通过构成中枢神经系统综合评估的病理变化任意量表分别和综合评估检查结果。结果表明中枢神经系统有相当程度的恶化,这是功能性病理变化的反映。5年后,这种对接触工人中枢神经系统的综合评估方式显示,与对照组相比,接触工人出现了明显更多的病理变化。在20名在中枢神经系统评估中结果最差的接触男性中,进行了头部计算机断层扫描。在60%的上述人员中发现了皮质和/或皮质下萎缩,大多数人的萎缩程度较小。同时需要指出的是,上述中枢神经系统检查能够早期评估职业性接触低浓度二硫化碳人群的中枢神经系统功能和形态状态。

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