Corbineau H, Logeais Y, Chaperon J, Rioux C, Leguerrier A, Lecheaux D, Langanay T, Sevray B
Clinique chirurgicale cardiovasculaire et thoracique, hôpital Pontchaillou, CHU, Rennes.
Arch Mal Coeur Vaiss. 1995 Jun;88(6):855-60.
Between April 1974 and November 1992, 181 patients were operated for aneurysm (106) or dissection (75) of the ascending aorta. Eighty patients had replacement with a valvular conduit with reimplantation of the coronary arteries (Bentall procedure), 48 had aortic valve replacement with replacement of the supra-coronary ascending aorta and 53 underwent isolated replacement of the ascending aorta. Twenty-nine patients (16%) died in the postoperative period, mainly of myocardial or neurological complications. Univariate statistical analysis completed by logistic regression analysis revealed the following predictive factors of early death: NYHA Stage IV, angina, reoperation for haemorrhage or tamponade (all < 0.05). All surviving patients were followed up (total follow-up: 788 years; mean: 62 months; range: 1 to 181 months). There were 20 secondary deaths, 40% of which were related to complications of aortic valve replacement. The 5 and 9 year survivals were 76 and 70% respectively, perioperative mortality included, and 89% of patients were in NYHA functional Stage I. Analysis of survival data did not reveal any predictive factor of secondary death. Eight patients were reoperated at long-term. The operative mortality of replacement of the ascending aorta remains high, especially in cases of dissection. The long-term results seem excellent with a low reoperation rate. Late mortality seems mainly due to complications of aortic valve replacement.
1974年4月至1992年11月期间,181例患者接受了升主动脉瘤(106例)或夹层动脉瘤(75例)手术。80例患者采用带瓣管道置换并冠状动脉再植入术(Bentall手术),48例患者进行主动脉瓣置换并置换冠状动脉上方的升主动脉,53例患者接受单纯升主动脉置换。29例患者(16%)术后死亡,主要死于心肌或神经并发症。通过逻辑回归分析完成的单因素统计分析显示了以下早期死亡的预测因素:纽约心脏协会(NYHA)IV级、心绞痛、因出血或心包填塞再次手术(均<0.05)。所有存活患者均接受随访(总随访时间:788年;平均:62个月;范围:1至181个月)。有20例继发死亡,其中40%与主动脉瓣置换并发症有关。围手术期死亡率包括在内的5年和9年生存率分别为76%和70%,89%的患者处于NYHA功能I级。生存数据分析未显示任何继发死亡的预测因素。8例患者在长期随访中接受了再次手术。升主动脉置换的手术死亡率仍然很高,尤其是在夹层动脉瘤病例中。长期结果似乎很好,再次手术率很低。晚期死亡率似乎主要归因于主动脉瓣置换并发症。