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[特应性皮炎(AD)患者家中螨虫调查及除螨后的临床改善情况]

[Investigation of mites in the houses of atopic dermatitis (AD) patients, and clinical improvements by mite elimination].

作者信息

Kumei A

机构信息

Department of Hygiene and Public Health, Tokyo Women's Medical College.

出版信息

Arerugi. 1995 Mar;44(3 Pt 1):116-27.

PMID:7646368
Abstract

Seasonal variations related to mites were investigated by the Methylene Blue Agar (MBA) method in the houses of 157 AD patients living in Tokyo. Many mites were counted in the dust from carpets, Japanese straw mats (Tatami) and the floor under Tatami. In most places, the number of mites was found to increase in summer. In winter, however, mite levels increased in sofas and Japanese seat cushions. On the other hand, only small numbers of mites were found in mite-proof products. Based on the above data, were recommended mite elimination by various scientific techniques was recommended for 34 severe AD patients. Mite levels and clinical symptoms were again checked after one year and two years in the same seasons. In 17 of the 34 cases, mite elimination was carried out completely. In these cases, the ratio of mite decrease to less than 30% was 82%, and the ratio of improvement of clinical symptoms (remarkable improvement + improvement) was 88%. Almost complete cure was noted in 7 cases. On the other hand, in the remaining 17 cases, mite elimination was performed incompletely in 12 cases, and was hardly done at all in 5 cases. The ratio of mite decrease to less than 30% was 47%, and the ratio of improvement of clinical symptoms was 35%. Therefore, it was concluded that investigation of mite levels following mite elimination procedures is a most recommendable treatment for severe AD patients who are hypersensitive to house dust mites.

摘要

采用美蓝琼脂(MBA)法,对居住在东京的157例特应性皮炎(AD)患者家中与螨虫相关的季节性变化进行了调查。在地毯、榻榻米和榻榻米下面的地板灰尘中发现了许多螨虫。在大多数地方,螨虫数量在夏季增加。然而,在冬季,沙发和日式坐垫中的螨虫数量增加。另一方面,在防螨产品中仅发现少量螨虫。基于上述数据,建议对34例重度AD患者采用各种科学技术清除螨虫。在相同季节的一年和两年后,再次检查螨虫水平和临床症状。在34例患者中的17例中,螨虫被完全清除。在这些病例中,螨虫减少至30%以下的比例为82%,临床症状改善的比例(显著改善+改善)为88%。7例患者几乎完全治愈。另一方面,在其余17例中,12例螨虫清除不完全,5例几乎未进行清除。螨虫减少至30%以下的比例为47%,临床症状改善的比例为35%。因此,得出结论,对于对屋尘螨过敏的重度AD患者,在清除螨虫程序后调查螨虫水平是最值得推荐的治疗方法。

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Arerugi. 1995 Mar;44(3 Pt 1):116-27.
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