Woods D R
Microbiology Department, University of Cape Town, Rondebosch, South Africa.
Trends Biotechnol. 1995 Jul;13(7):259-64. doi: 10.1016/S0167-7799(00)88960-X.
Although the production of acetone and butanol by Clostridium strains was a thriving industrial fermentation process, it is no longer competitive with the chemical synthesis of solvents and has been discontinued. However, studies on the molecular biology of Clostridium strains suggest that genetic engineering for improved solvent production is feasible, and could result in the revival of the industrial fermentation process.
尽管梭菌属菌株生产丙酮和丁醇曾是一个蓬勃发展的工业发酵过程，但它已不再能与溶剂的化学合成相竞争，并且已被停产。然而，对梭菌属菌株分子生物学的研究表明，通过基因工程提高溶剂产量是可行的，这可能会使工业发酵过程得以复兴。
