Charlton C A, Crowther A, Davies J G, Dynes J, Haward M W, Mann P G, Rye S
Br Med J. 1976 Jan 17;1(6002):124-6. doi: 10.1136/bmj.1.6002.124.
The length of a course of antibiotic treatment for urinary tract infection varies with the habits of the prescriber. Many patients do not complete a course of treatment once their symptoms have subsided. In uncomplicated urinary tract infection among women seen in general practice a three-day course of amoxycillin was as effective as a 10-day course of the same drug in the same dose. Relief of symptoms was equal in both groups and bacteriuria was eliminated equally successfully in both regimens. There was no significant difference between the two groups in the incidence of side effects from the drugs. The financial saving which could accrue from adopting this therapeutic regimen would be significant.
尿路感染抗生素治疗疗程的长短因开处方医生的习惯而异。许多患者症状一旦缓解就不再完成整个疗程的治疗。在全科医疗中所见到的非复杂性女性尿路感染患者中,服用相同剂量阿莫西林进行为期三天的疗程与为期十天的疗程疗效相同。两组患者症状缓解情况相同,两种治疗方案在消除菌尿方面同样成功。两组药物副作用的发生率没有显著差异。采用这种治疗方案可节省的费用将是可观的。