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全科医疗中针对尿路感染的三日和十日化疗方案。

Three-day and ten-day chemotherapy for urinary tract infections in general practice.

作者信息

Charlton C A, Crowther A, Davies J G, Dynes J, Haward M W, Mann P G, Rye S

出版信息

Br Med J. 1976 Jan 17;1(6002):124-6. doi: 10.1136/bmj.1.6002.124.

DOI:10.1136/bmj.1.6002.124
PMID:764915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1638616/
Abstract

The length of a course of antibiotic treatment for urinary tract infection varies with the habits of the prescriber. Many patients do not complete a course of treatment once their symptoms have subsided. In uncomplicated urinary tract infection among women seen in general practice a three-day course of amoxycillin was as effective as a 10-day course of the same drug in the same dose. Relief of symptoms was equal in both groups and bacteriuria was eliminated equally successfully in both regimens. There was no significant difference between the two groups in the incidence of side effects from the drugs. The financial saving which could accrue from adopting this therapeutic regimen would be significant.

摘要

尿路感染抗生素治疗疗程的长短因开处方医生的习惯而异。许多患者症状一旦缓解就不再完成整个疗程的治疗。在全科医疗中所见到的非复杂性女性尿路感染患者中,服用相同剂量阿莫西林进行为期三天的疗程与为期十天的疗程疗效相同。两组患者症状缓解情况相同,两种治疗方案在消除菌尿方面同样成功。两组药物副作用的发生率没有显著差异。采用这种治疗方案可节省的费用将是可观的。

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Three-day and ten-day chemotherapy for urinary tract infections in general practice.全科医疗中针对尿路感染的三日和十日化疗方案。
Br Med J. 1976 Jan 17;1(6002):124-6. doi: 10.1136/bmj.1.6002.124.
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Treatment of urinary-tract infection with a single dose of amoxycillin.
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Three-day and one-day chemotherapy for urinary tract infections in general practice.
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Controlled randomized study comparing amoxycillin and pivmecillinam in adult out-patients presenting with symptoms of acute urinary tract infection.
J Antimicrob Chemother. 1977 Jul;3 Suppl B:121-7. doi: 10.1093/jac/3.suppl_b.121.
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Asymptomatic bacteriuria and symptomatic urinary tract infections (UTI) in patients with diabetes mellitus in Tikur Anbessa Specialized University Hospital, Addis Ababa, Ethiopia.埃塞俄比亚亚的斯亚贝巴提库尔安贝萨专科医院糖尿病患者的无症状菌尿和有症状的尿路感染
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N Z Med J. 1978 Oct 25;88(622):317-20.
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New directions in the diagnosis and therapy of urinary tract infections.尿路感染诊断与治疗的新方向
Am J Obstet Gynecol. 1991 May;164(5 Pt 2):1387-9. doi: 10.1016/0002-9378(91)91478-f.
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[Amoxicillin in the management of urinary tract infections].
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PLoS Comput Biol. 2016 Apr 14;12(4):e1004857. doi: 10.1371/journal.pcbi.1004857. eCollection 2016 Apr.
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"One-size-fits-all"? Optimizing treatment duration for bacterial infections.“一刀切”?优化细菌感染的治疗持续时间。
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Single-dose antibiotic treatment: a new approach to lower urinary tract infections in primary care.单剂量抗生素治疗:初级保健中降低下尿路感染的新方法。
Can Fam Physician. 1981 Jan;27:143-5.
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Antibiotic duration for treating uncomplicated, symptomatic lower urinary tract infections in elderly women.老年女性单纯性、有症状下尿路感染的抗生素治疗疗程
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Incidence and remission of lower urinary tract symptoms. Authors should have used standardised questionnaire.下尿路症状的发病率和缓解情况。作者应使用标准化问卷。
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Short-term treatment of lower urinary tract infections in children with trimethoprim/sulphadiazine.用甲氧苄啶/磺胺嘧啶对儿童下尿路感染进行短期治疗。
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Trial of three-day and ten-day courses of amoxycillin in otitis media.阿莫西林治疗中耳炎三日和十日疗程的试验
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Effective treatment of urinary tract infections.尿路感染的有效治疗。
Infection. 1980;Suppl 1:70-4. doi: 10.1007/BF01644939.

本文引用的文献

1
PRESENTATION, DIAGNOSIS, AND TREATMENT OF URINARY-TRACT INFECTIONS IN GENERAL PRACTICE.一般实践中尿路感染的表现、诊断及治疗
Lancet. 1965 Mar 6;1(7384):514-6. doi: 10.1016/s0140-6736(65)92020-9.
2
ACUTE INFECTIONS OF THE URINARY TRACT AND THE URETHRAL SYNDROME IN GENERAL PRACTICE.全科医疗中的急性尿路感染及尿道综合征
Br Med J. 1965 Mar 6;1(5435):622-6. doi: 10.1136/bmj.1.5435.622.
3
Laboratory diagnosis of infections of the urinary tract in general practice by means of a dip-inoculum transport medium.通过浸种转运培养基对全科医疗中尿路感染进行实验室诊断。
Br Med J. 1965 Nov 27;2(5473):1286-8. doi: 10.1136/bmj.2.5473.1286.
4
Multicentre survey of urinary tract infections in general practice. Clinical trial of single dose treatment with sulfametopyrazine (Kelfizine-W).
Br J Urol. 1972 Feb;44(1):105-9. doi: 10.1111/j.1464-410x.1972.tb12120.x.
5
Antibiotic resistance of coliform bacilli in urinary infection acquired by women outside hospital. A 12-year survey.
Lancet. 1971 Sep 25;2(7726):675-7. doi: 10.1016/s0140-6736(71)92246-x.