Fahal A H, el Toum E A, el Hassan A M, Mahgoub E S, Gumaa S A
Department of Surgery, Faculty of Medicine, University of Khartoum, Sudan.
J Med Vet Mycol. 1995 Jan-Feb;33(1):15-7.
In this prospective study, three types of tissue reaction to mycetoma grains are described. Type I reaction is characterized by the adherence of neutrophils to the surface of the grain leading to its disintegration. In Type II reaction, the fragmented grain and the dead neutrophils are cleared by macrophages and multinucleated giant cells, while in Type III reaction there is a discrete well developed epithelioid granuloma with Langhans's giant cells. The three types of reaction are usually seen in different combinations in the same lesion.
在这项前瞻性研究中，描述了对足菌肿颗粒的三种组织反应类型。I型反应的特征是中性粒细胞粘附于颗粒表面，导致其崩解。在II型反应中，破碎的颗粒和死亡的中性粒细胞被巨噬细胞和多核巨细胞清除，而在III型反应中，有一个离散的、发育良好的上皮样肉芽肿，伴有朗汉斯巨细胞。这三种反应类型通常在同一病变中以不同组合出现。
